Extended Data Fig. 9: Ethological analyses of social behaviour and preservation statistics from the DREADD iDISCO+ experiment.
From: A crucial role for the cortical amygdala in shaping social encounters
a–c, Inhibiting COAplEsr1 cells results in a reduction in bites (t25 = 3.883, p = 0.0007, a) and kicks (t25 = 2.11, p = 0.0450, b) delivered to the intruder with no effect on wrestling (t25 = 1.708, p = 0.0863, c) compared to the mCherry group. d–f, Mice injected with the hM4Di virus also displayed an increase in anogenital (t25 = 4.441, p = 0.0002, d), facial (t25 = 2.718, p = 0.0118, e) and flank (t25 = 3.496, p = 0.0018, f) investigation n = 13 hM4Di, 14 mCherry. g, In addition to the pink module, inhibiting the COApl alters the preservation of the red module (t9 = 3.600, q = 0.022980). h, The pink module had the highest percentage of regions (85%) which showed a decrease in FOS. All data are mean ± s.e.m.
