Extended Data Fig. 3: AlphaFold2 pTM correlation.
From: Protein structure prediction with in-cell photo-crosslinking mass spectrometry and deep learning
Calibration of the predicted TM-score (pTM) on N = 320 predictions of the E. coli membrane fraction dataset. On predictions that are at least 80% covered by the crystal structure, the correlation is 0.91. The true TM-score is generally underestimated, meaning that the pTM-score of AlphaFold2 is a conservative estimate. The shaded area corresponds to the 95% confidence interval. Line shows the linear fit.
