Extended Data Fig. 2: The editing efficiencies of various prime editors. | Nature Biotechnology

Extended Data Fig. 2: The editing efficiencies of various prime editors.

From: Prime editing using CRISPR-Cas12a and circular RNAs in human cells

Extended Data Fig. 2

a, Efficiencies of prime editing of various prime editors with Cas9 or nCas9 (H840A) and linear RNA (LinRNA) or circular RNA (CircRNA) at the FANCF site in HEK293T cells. b, Efficiencies of prime editing of these prime editors with Cas12a (D156R) or nCas12a (D156R-R1138A) and LinRNA or CircRNA at the DNMT1-T3 site. Efficiencies (mean ± s.d.) were calculated from three independent experiments (n = 3) in a, b. RTΔR, M-MLV RTΔRNase H.

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