Extended Data Fig. 1: Quantile-quantile (QQ) plots.
From: Comparative genetic architectures of schizophrenia in East Asian and European populations
a-p, QQ plots for two-tailed logistic regression in each EAS stage 1 sample (a-m) and fixed effect inverse variance meta-analyses including all EAS stage 1 samples (n), stages 1 and 2 samples (o), and all EUR and EAS (stages 1 and 2) samples (p). Blue line indicates the expected null distribution, and the shaded area indicates the 95% confidence interval of the null distribution. Legend: “lambda” = genomic inflation factor; “lambda1000” = genomic inflation factor for an equivalent study of 1,000 cases and 1,000 controls; “N(pvals)” = number of variants used in the plot. Autosomal variants that have minor allele frequency ≥ 1% and INFO ≥ 0.6 from imputation were included. Observed P-values were capped at 10-12 for visualization purposes.
