Extended Data Fig. 5: Genomic structure of contigs derived from optical mapping data of seismic amplicons in cell line LS.
From: Chromothripsis followed by circular recombination drives oncogene amplification in human cancer
Visualization of optical mapping data of seismic amplicons in neuroblastoma cell line LS. Contigs derived from the amplicon harboring rearranged genomic fragments of affected chromosomes (bottom) are shown in comparison to the copy number and rearrangement profile inferred from WGS data (top). Black arrows in the contigs indicate orientation of genomic fragments. CN, copy number; RA, rearrangement.
