Extended Data Fig. 5: ecDNA heterogeneity in patient tumours. | Nature Genetics

Extended Data Fig. 5: ecDNA heterogeneity in patient tumours.

From: The evolutionary dynamics of extrachromosomal DNA in human cancers

Extended Data Fig. 5

a, Histograms of ecDNA copy number assessed by interphase FISH on patient tumor tissue from neuroblastoma (NB) patients with MYCN amplification. b, Quantile-quantile plots for ecDNA copy number comparing measured ecDNA number from patient tissue FISH and simulated ecDNA number from simulated tumour growth.

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