Extended Data Fig. 8: Metabolic and anthropometric attributes of mmΔSnx10^Adipoq mice and control littermates.

* indicates p < 0.01. All statistical tests are two-sided Student’s t-tests between sex-genotype groups. F-control n = 12 mice, F-KO n = 5, M-control n = 34 M-KO n = 6 in all tests. Box plot whiskers represent minimum (1^st percentile) and maximum (99^th percentile) of data, box bounds represent first quartile (25^th percentile and 75^th percentile), and center line represents median of data (50^th percentile). a) Mass of body fat of ^{mmΔSnx10Adipoq} mice and littermate controls by sex. b) Femur length of mmΔSnx10^Adipoq mice and littermate controls by sex. c) Lean mass of mmΔSnx10^Adipoq mice and littermate controls by sex. d) Lean percent of mmΔSnx10^Adipoq mice and littermate controls by sex. Data are colored by sex and SNX10 genotype. Fat weight:Mean FC = 19.6, mean FKO = 7.50, mean MC = 19.0, mean MKO = 20.9. FKO vs MKOt=5.90, df=4, CI = 7.33-19.5. Lean weight:Mean FC = 20.3, mean FKO = 17.8, mean MC = 25.4, mean MKO = 26.5. FKO vs MKO t = 8.48,df=4,CI = -5.45-11.1. Lean body fat percent:Mean FC = 49.7, mean FKO = 72.2, mean MC = 56.3, mean MKO = 55.0. FKO vs MKO) t = -6.27,df=4,CI = -24.1–10.4. Femur length:Mean FC = 1.6, mean FKO = 1.5, mean MC = 1.7, mean MKO = 1.7. FKO vs MKO t = 1.75,df=4,CI = -0.0810-0.436.