Extended Data Fig. 1: Overview of the MPM datasets for multiomic integration with MOFA. | Nature Genetics

Extended Data Fig. 1: Overview of the MPM datasets for multiomic integration with MOFA.

From: Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity

Extended Data Fig. 1

Overview of the omic data sets integrated into multiomics factor analyses (MOFAs), for (a) a MOFA of the MESOMICS cohort (n = 120), (b) MOFA of the TCGA cohort (n = 73), (c) MOFA of the Bueno cohort (n = 181), and (d) MOFA of the 3 cohorts (n = 120 + 73 + 181). D is the number of integrated omic features from genomic (rearrangements and mutations within DNA Alt; allele-specific copy number (CN) in Total CN and Minor CN), transcriptomic (RNA), and epigenomic data at promoter (MethPro), gene body (MethBod), and enhancer regions (MethEnh).

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