Extended Data Fig. 8: Mechanistic model of protein kinase fusion proteins in plant disease resistance.
From: The wheat stem rust resistance gene Sr43 encodes an unusual protein kinase
The protein kinase (PK) fusion protein contains an integrated decoy (ID) that traps the avirulence effector protein (red square). This triggers an autophosphorylation of either the protein kinase or decoy, the effector, or the nucleotide binding leucine-rich repeat (NLR) guard. This results in a conformational change which in turn triggers a signal cascade leading to downstream defense responses and immunity.
