Fig. 1: The origin and genomic composition of the 142 ScRAP strains.

a, Ecological origin, ploidy and zygosity description of the 142 ScRAP strains. Colors are used as keys to symbolize the strain origin (wild (green), domesticated (red), human (blue) or laboratory (yellow)) and shapes symbolize their ploidy and zygosity levels (haploid (one-slice half circle), homozygous diploid (full circle), heterozygous diploid (two-sliced circle), heterozygous triploid and tetraploid (three- and four-sliced circle). The haploid category contains both natural and engineered (Δho) strains. All triploid and tetraploid strains are heterozygous except for the homozygous triploid strain isolated in the USA. b, Geographical origin of the isolates. The shape and colors of the symbols are as in a. c, Phylogenetic tree based on the concatenated protein sequence alignment of 1,612 1:1 orthologs. The tree was rooted by including 23 strains from other Saccharomyces species (not presented in the figure). The symbols on the right recall the ecological origin, ploidy and zygosity of all isolates, as described in a. The presence of aneuploid chromosomes is labeled by an asterisk with varying gray levels discriminating between several cases relative to the 1,011 genome survey³¹—black, previously detected; dark gray, not previously detected; middle gray, previously absent and newly gained; light gray, previously present but newly lost. d, Genetic ancestry of the population as defined by running ADMIXTURE with k = 13.