Fig. 3: Structure and prevalence of complex aneuploidies.
a, Schematics representing the chromosomal composition of complex aneuploidies. The red dots symbolize centromeres. The gray boxes indicate the translocation breakpoints. Dotted framings show duplicated regions, while dotted lines within chromosomes indicate deletions. The black box in ASB symbolizes the HGT region. b, Distribution of the sizes of chromosomes involved in complex (n = 85 different chromosomes) vs simple (n = 379 different chromosomes) aneuploidies. The horizontal lines in the boxplots correspond to the median, the lower and upper hinges correspond to the first and third quartiles and the whiskers extend up to 1.5 times the interquartile range. Two-sided Wilcoxon mean comparison P values are indicated. c, Percentage of the total chromosome aneuploidies that are complex as a function of their size. The coefficient of determination (r2) was calculated with the lm method of the R program. The shaded error band represents the 95% confidence interval of the regression fit. d, Number and percentage of euploid, simple and complex aneuploid among 993 analyzed strains.
