Extended Data Fig. 2: Calibration in different non-sparsity coverage settings.
From: Improving fine-mapping by modeling infinitesimal effects
Calibration for SuSiE, SuSiE-inf, FINEMAP and FINEMAP-inf in simulations with different non-sparsity coverage settings: 0.5%, 1%, and 5% (see Table 1 for more parameter settings in these simulations). Heritability ratio between small and large effects is fixed at 3:1 for three simulation scenarios, while the fourth scenario we set the coverage at 5% and heritability ratio at 15:1 to match the per-SNP heritability in simulations where 1% SNPs are causal and heritability ratio is 3:1. Error bars correspond to 95% Wilson confidence interval. Numerical results available in Supplementary Table 15.
