Extended Data Fig. 5: Estimated effect of metastatic sample on tumor mutational burden and fraction of genome altered by cancer subtype. | Nature Genetics

Extended Data Fig. 5: Estimated effect of metastatic sample on tumor mutational burden and fraction of genome altered by cancer subtype.

From: Longitudinal and multisite sampling reveals mutational and copy number evolution in tumors during metastatic dissemination

Extended Data Fig. 5

(a, b) Subtype analysis of infiltrating ductal carcinoma, and the estimated effect of metastatic sample on TMB and FGA. HR = hormone receptor. (c, d) Subtype analysis of pancreatic cancer, and the estimated effect of metastatic sample on TMB and FGA. NET = neuroendocrine tumor. (e, f) Subtype analysis of non-small cell lung cancer, and the estimated effect of metastatic sample on TMB and FGA. The plots show the point estimate (dot), with the whiskers representing the 95% confidence interval. FGA = fraction of genome altered.

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