Extended Data Fig. 10: Evaluation of LptD-thanatin interaction stability.
From: Dynamics of an LPS translocon induced by substrate and an antimicrobial peptide
a, RMSD of thanatin docked to the bottom (i) of the β-jellyroll in its closed conformation compared to being docked to the top (ii) where standard deviation is colored gray. b, Right: schematic showing the orientation of the β-taco vector drawn through Cα of residues Asp33 and Pro190, where x, y displacement is shown as red arrows. Right: x,y displacement of the β-taco vector mapped relative to the origin 0.0, 0.0 (defined as the original position of β-taco in the crystal structure) comparing the conformation space sampled of the apo-β-taco against when thanatin is docked to the (i) bottom and (ii) top of the β-taco.
