Extended Data Fig. 5: Location of TM1 residues that are accessible by sulfhydryl reagent.
From: Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily
Residues accessible in closed state are shown as yellow sticks, whereas residues accessible from intracellular side in open state are shown as blue sticks (equivalent residues in the original HaFaNaC are shown in parentheses in a). Trp 95, whose mutation to cysteine resulted in a nonfunctional channel, is shown as green sticks. Front (a) and top (b) views are shown.
