Extended Data Fig. 4: Quantification of NFAT-dependent luciferase expression under the indicated conditions.
From: Repurposing salicylic acid as a versatile inducer of proximity
Measurement of NFAT-Luc reporter activity was performed in Jurkat T cells with stable expression of the indicated constructs. Engineered Jurkat cells were co-cultured with human CD19 (hCD19)-positive Raji lymphoma cells (indicated by solid blue circle) or hCD19-negative K562 cells (open blue circle), in the absence (open red square) or presence (solid red square) of 500 µM SA. Anti-HER2 CAR and Anti-HER2 SAMBA-CAR were used as control groups. n = 3 independent biological replicates (mean ± s.e.m.).
