Supplementary Figure 8: Nfkb2Lym1/+ mice have impaired host defense against C. rodentium infection.
From: NIK signaling axis regulates dendritic cell function in intestinal immunity and homeostasis
a–d, Body weight change (a), colon length (b), C. rodentium bacterial load in spleen, liver and feces (c), and histological analysis of H&E-stained colon tissue (d) of wild-type (WT) and Nfkb2Lym1/+ mice infected orally with 4 × 109 CFUs of C. rodentium (n = 4 per genotype). Scale bar, 200 μm. Each symbol represents an individual mouse, and small horizontal lines indicate the mean ( ± s.e.m.) (b,c). Data were analyzed by two-way ANOVA followed by Sidak’s multiple-comparisons test (a) or unpaired two-tailed Student’s t test (b,c). Data are representative of two independent experiments. P values are shown above plots. For a, **P = 0.006, ***P < 0.001 and ###P < 0.001.
