Extended Data Fig. 1: γδ T cells, but not conventional T cells, are a positive prognosis factor for survival in brain cancer patients.
From: Tumor hypoxia represses γδ T cell-mediated antitumor immunity against brain tumors
Analysis of brain cancer patient survival according to TCGA data. a, Overall survival of brain cancer patients grouped according to high or low expression compared to median value of CD4 (n = 347 (low), 349 (high)) and CD8A (n = 348 (low), 347 (high)) of GBMLGG. b, Overall survival of LGG (Low-grade glioma) patients grouped by high or low expression compared to quartile value of CD4 (n = 132 (low), 130 (high)), CD8A (n = 130 (low), 131 (high)) and TRGC1 (n = 130 (low),130 (high)). c, Overall survival of GBM (Glioblastoma multiforme, one of high-grade glioma, HGG) patients grouped by quartile value of CD4 (n = 38 (low), 42 (high)), CD8A (n = 42 (low), 40 (high)) and TRGC1 (n = 43 (low), 37 (high)). (c). Survival data were analyzed by log-rank test. d, Gating scheme for analysis of flow cytometry for engineered HGG mice model. FVD450, Fixable viability dye 450.
