Extended Data Fig. 8: scATAC-seq from the melanoma validation cohort.
a. Plot shows the peak accessibility within myeloid cells in the IRC high and low patient groups for IDO1. Gene track and called peaks are shown below each peak map. b. Differential transcription factor binding motifs enriched in open chromatin regions of CD8 Teff cells from IRC low (top, blue) and IRC high (bottom, red) patients. P value determined by two-sided Wilcoxon’s rank-sum test and adjusted with the Bonferroni correction.
