Extended Data Fig. 9: Flow cytometry assessment of colonic lamina propria immune cells. | Nature Immunology

Extended Data Fig. 9: Flow cytometry assessment of colonic lamina propria immune cells.

From: Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation

Extended Data Fig. 9

(a, b) Flow cytometry comparison of colonic lamina propria (a) myeloid (Mann-Whitney U test, unpaired t test, *P = 0.0481, unpaired t test, *P = 0.0109) and (b) lymphocyte cell populations between Nlrp10D/D and Nlrp10loxP/loxP littermate mice at day 4 after DSS initiation (n = 5) (unpaired t test, Mann- Whitney U test). (c, d) Flow cytometry Comparison of colonic lamina propria (c) myeloid cell (unpaired t test, *P = 0.0135, **P = 0.0096) and (d) lymphocyte (unpaired t test, *P = 0.0184, **P = 0.0095, **P = 0.005, Mann-Whitney U test, *P = 0.0159) populations between Nlrp10D/D and Nlrp10loxP/loxP littermate mice at day 7 after DSS initiation (Nlrp10loxP/loxP n = 5; Nlrp10D/D n = 4). Mean ± SEM. *: p < 0.05, **: p < 0.01. Statistical test used in (a- d) was two-sided.

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