The National Institute of Allergy and Infectious Diseases (NIAID) hosted a symposium on ‘AI and Immunology: Exploring Challenges and Opportunities’. The event considered how artificial intelligence (AI) can advance research on the multi-scale, adaptive immune system to improve human health, covering basic research and clinical use cases, data and AI model fundamentals.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
27,99 € / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
209,00 € per year
only 17,42 € per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout

References
Gallifant, J. et al. PLoS Digit. Health 3, e0000417 (2024).
Sparks, R. et al. Nat. Med. 30, 2461–2472 (2024).
Nakaya, H. et al. Nat. Immunol. 12, 786–795 (2011).
Gentili, M. et al. Preprint at bioRxiv https://doi.org/10.1101/2024.04.07.588166 (2024).
Zhang, F. et al. Nature 623, 616–624 (2023).
Pandey, G. et al. Sci Rep. 8, 8826 (2018).
Christley, S. et al. Front. Immunol. 12, 624230 (2021).
Hédou, J. et al. Nat. Biotechnol. https://doi.org/10.1038/s41587-023-02033-x (2024).
Connors, T. J. et al. Immunity 56, 1894–1909.e5 (2023).
Aevermann, B. D. et al. Front. Immunol. 12, 690470 (2021).
Wang, M., Patsenker, J., Li, H., Kluger, Y. & Kleinstein, S. H. Nucleic Acids Res. 52, 548–557 (2024).
Peng, C. et al. npj Digit. Med. 6, 210 (2023).
Fang, Y. et al. J. Biomed. Inf. 142, 104375 (2023).
Laubenbacher, R., Adler, F. & An, G. Front. Digit. Health https://doi.org/10.3389/fdgth.2024.1349595 (2024).
Berson, E. et al. Nat. Methods 21, 1400–1402 (2024).
Acknowledgements
We thank all symposium participants who attended in person and online for their expertise, insights and stimulating discussions during the symposium. We are deeply indebted to Q. Chen, S. Kleinstein and L. Buyon for their service on the organizing committee, and L. Biven, L. G. Cowell, B. Peters and V. Shanmugam for their service as session chairs. We extend our gratitude to the speakers and panelists at the symposium. This work was supported in part by the Intramural Research Program of the National Library of Medicine (NLM), and the NIAID, NIH.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing ineterests
All authors have no competing interests.
Rights and permissions
About this article
Cite this article
Gururaj, A.E., Scheuermann, R.H. & Lin, D. AI and immunology as a new research paradigm. Nat Immunol 25, 1993–1996 (2024). https://doi.org/10.1038/s41590-024-01974-y
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41590-024-01974-y