Supplementary Figure 4: Intact DHPG-induced LTD in GluA2C1KI mice | Nature Neuroscience

Supplementary Figure 4: Intact DHPG-induced LTD in GluA2C1KI mice

From: The C-terminal tails of endogenous GluA1 and GluA2 differentially contribute to hippocampal synaptic plasticity and learning

Supplementary Figure 4

(a) Lack of effect of AP5 on DHPG-LTD (WT = 75.81 ± 5.33%, n = 4 slices from 4 mice; A2C1KI = 67.52 ± 4.75%, n = 4 slices from 4 mice, t(6) = 1.161, p = 0.290). (b) Blockade of DHPG-LTD by MPEP (WT = 111.37 ± 5.70%, n = 4 slices from 4 mice; A2C1KI = 118.55 ± 9.49%, n = 4 slices from 4 mice, t(6) = −0.648, p = 0.541). Two-tailed t-test at 95% confidence interval. Scale bar: 50 pA/25 ms. Data were presented as mean ± s.e.m.

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