Supplementary Figure 11: Analysis of cINs transplanted in the cortex of Nod Scid mice.

Related to Fig. 7. The lines used are summarized in Supplementary Table 3 (a) Immunocytochemistry analysis of cINs transplanted in the cortex of Nod Scid mice after 7 months’ grafting (scale bar = 50 µm). Proportion of PV+ neurons among NCAM+ neurons between groups (n = 100 NCAM+ neurons, p = 0.7883, chi-square test). (b) GABAergic synapse analysis of healthy control versus schizophrenia cINs (n = 14 images, scale bar = 5 µm). (c) Glutamatergic synapse analysis of healthy control versus schizophrenia cINs (n = 14 images, scale bar = 5 µm). (d) Linear regression model of PCDHA expression level in cINs (x-axis) and number of inhibitory synapses (juxtaposed GFP+ VGAT+ puncta and Gephyrin+ puncta) per 100 µm2 of GFP+ cINs (y-axis). n = 14 lines.