Supplementary Figure 4: Mendelian randomization test for a putative causal effect of depression (n = 629,934 individuals; 56 instrumental variables) on neuroticism (n = 29,496 twin pairs) using inverse weighted regression, MR Egger and a weighted median test. | Nature Neuroscience

Supplementary Figure 4: Mendelian randomization test for a putative causal effect of depression (n = 629,934 individuals; 56 instrumental variables) on neuroticism (n = 29,496 twin pairs) using inverse weighted regression, MR Egger and a weighted median test.

From: Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

Supplementary Figure 4

Center values reflect the effect of each instrumental variable on each trait with the respective error bars reflecting the standard error of the variable’s effect on each trait.

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