Supplementary Figure 6: Mendelian randomization test for a putative causal effect of neuroticism (n = 329,821 individuals; 65 instrumental variables) on depression (n = 537,701 individuals) using inverse weighted regression, MR Egger and a weighted median test.

Center values reflect the effect of each instrumental variable on each trait with the respective error bars reflecting the standard error of the variable’s effect on each trait.