Supplementary Figure 8: CRISPR-mediated overexpression of Zfp189 in N2A cells.
From: Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex
a) Targeting dCas9 with no functional ___domain to the Zfp189 promoter does not affect Zfp189 expression (U = 4.0, p = 0.343, n = 4). b) Targeting dCas9 fused to phosphomimetic CREBS133D increases Zfp189 (U = 1.0, p = 0.009, n = 5,6). c) Localizing dCas9 fused to a phospho-null CREBS133A does not affect Zfp189 expression (t=0.9868, p = 0.362, n = 4).
