Extended Data Fig. 6: Additional immunohistochemical characterization of α-syn inclusions in TgM83 mice inoculated with the S or NS fibril-derived strains.
From: α-Synuclein strains target distinct brain regions and cell types
Representative immunohistochemistry images for either PSyn (midbrain), PK-resistant total α-syn (hypothalamus), or p62 (midbrain) in brain sections from clinically ill TgM83 mice inoculated with either the S fibril- or NS fibril-derived strains (first or second passage). Scale bar = 10 μm (applies to all images). For each experimental group, stainings were performed on a minimum of two mice with similar results.
