Extended Data Fig. 3: Freely moving fiber photometry recordings of GRABNE and astrocyte Ca2+.
From: Norepinephrine links astrocytic activity to regulation of cortical state
(a) Schematic of fiber photometry recording set-up. (b) A 5-minute example fiber photometry recording of GRABNE signal. (c) GRABNE power spectrum. n = 4 mice, 19 recordings over multiple days, 10–30 minutes/recording. Error lines are ± s.e.m. across all mice.) (d) GRABNE (green) and astrocyte jRGECO1b (magenta) signals evoked by startle responses due to tail lifts (grey arrow heads). (e) Average startle-response evoked traces for GRABNE and jRGECO, aligned to onset of astrocyte Ca2+. n = 4 mice, 4 tail lifts per mouse. Error is ± s.e.m. across mice.
