Fig. 3: Spatial distribution of subtype-specific locomotion responses. | Nature Neuroscience

Fig. 3: Spatial distribution of subtype-specific locomotion responses.

From: Unique functional responses differentially map onto genetic subtypes of dopamine neurons

Fig. 3

a, Comparison of locomotion response (cross-correlation between ΔF/F and acceleration) for Calb1 and Anxa1 recordings only from a region of striatum where their axons overlap, dashed red circle (1-mm diameter). Isosbestic controls in blue. Shaded areas denote mean ± s.e.m. Calb1 mice = 4, n = 5 recordings; Anxa1 mice = 5, n = 16 recordings. b, Locomotion response (PC1/PC2 angle, as shown in Fig. 2l) mapped onto recording ___location for each subtype and DAT. Locations from the body (top) or the tail of the striatum (bottom) were collapsed into a single brain section. To reduce overlap, locations were shifted a random amount between ±0.4 mm mediolaterally. See Extended Data Fig. 6a for an expanded version of this panel without shifts or collapsing slices together. Cross-corr, cross-correlation.

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