Extended Data Fig. 6: Extended data related to breathing and dACC→PnC activity measurements during EPM exposure.
From: A top-down slow breathing circuit that alleviates negative affect in mice
a, Illustrations showing GCaMP7s injection sites and fiber placement targeting dACC area, in mice used for elevated plus maze, elevated platform and foot shock exposure experiments (N = 6 mice). b, Representative traces of dACC→PnC neuronal activity (top) and breathing rate (bottom) during the elevated plus maze exposure. c, Representative raw breathing signals observed during an exit episode. d, Analysis of the length of inspiratory and expiratory phases before and after exit (N = 6 mice). e, Breathing rates during exploration of an exposed area classified by episodes with refrained behavior (n = 43 episodes) and full exploration (n = 10 episodes). ***P < 0.001. Data are shown as mean ± s.e.m. or individual value from each subject.
