Extended Data Fig. 5: Graphical representation of binding affinities.
From: Inactive and active state structures template selective tools for the human 5-HT5A receptor
a, Binding affinities of AS2674723 against the aminergic receptors. Data represent mean ± SEM of N = 3-10 replicates (N = 1 for muscarinic receptors (M1-M5)). b-c, Binding affinities of AS2674723 and LSD for WT and mutant 5-HT5ARs using 3H-LSD. See Supplementary Table 11 for fitted parameter values that represent mean ± SEM of N = 3 biological replicates.
