Figure 4 | Scientific Reports

Figure 4

From: miR-100-5p inhibition induces apoptosis in dormant prostate cancer cells and prevents the emergence of castration-resistant prostate cancer

Figure 4

Curated and predicted interaction network for miR-100-5p. (A) Three databases were used to find predicted gene and protein interactions with miR-100-5p. (B) Enriched canonical pathways using KEGG and GO pathway databases for predicted targets of miR-100-5p. Octagons represent major canonical pathways and associated genes, in red, are presented in round nodes circulating the pathways (generated using Cytoscape). (C) Gene networks regulated by miR-100-5p based on canonical pathways from GO and KEGG enrichment analyses associated with genes that are predicted to be regulated by miR-100-5p. (D) miR-100-5p expression in Taylor et al.32 MSKCC database finds a significant correlation between poor survival and alterations in target of miR-100-5p, MTOR.

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