Figure 1 | Scientific Reports

Figure 1

From: Endolysin LysEF-P10 shows potential as an alternative treatment strategy for multidrug-resistant Enterococcus faecalis infections

Figure 1

(A) Sequence alignment of LysEF-P10 and homologous proteins. The Cys-His-Asn triplet and putative calcium-binding residues are indicated by filled blue squares and filled blue diamonds, respectively. The blue and red arrows delineate the ends of the catalytic and binding domains, respectively. All alignments were obtained using CLUSTAL W (http://www.ch.embnet.org/software/ClustalW.html). The figure was mapped using ESPript (http://espript.ibcp.fr/ESPript/ESPript/index.php). Strictly conserved residues are boxed in white on a red background, and highly conserved residues are boxed in red on a white background. (B) Domain organisation of LysEF-P10. LysEF-P10 contains two domains: a CHAP ___domain (blue, residues 20–95) and a putative binding ___domain (red, residues 140–238). The figure also maps schematics of LysEF-P10C, LysEF-P10C-GFP, LysEF-P10B, and LysEF-P10B-GFP. The lytic or binding activity of these proteins is indicated with +/−.

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