Figure 5

GE triggered ER stress and activated IRE-1α pathway in HEY and A2780 cells. (A) The related proteins were examined by western blot. After transiently transfected with scramble or IRE-1α siRNA and treated with GE for 24 h, the cells were examined by annexin V/PI staining assay (B), and the proteins were examined by western blot (C). The full-length gels of western blot were shown in the Supplementary Information file. All experiments were performed at least three times.