Table 1 Radiation experiment process.

From: Thrombopoietic stimulating activity of rhTyrRS (Y341A)

Pre-treatment group

post-treatment group

 

D3-D1 before radiotherapy

D0

D1-D3 received radiotherapy

 

D1 before radiotherapy

D0

D1 received radiotherapy

D3-D5 received radiotherapy

PBS (negative control)

Mice were treated with PBS or rhTyrRS (Y341A) or TPO for three consecutive days before radiotherapy.

receive radiotherapy

Blood sampling in every day

PBS (negative control)

Blood sampling

receive radiotherapy

Blood sampling

Mice were treated with PBS or rhTyrRS (Y341A) or TPO for three consecutive days after radiotherapy.

rhTyrRS (Y341A) (1 μg/kg)

rhTyrRS (Y341A) (1 μg/kg)

rhTyrRS (Y341A) (10 μg/kg)

rhTyrRS (Y341A) (10 μg/kg)

rhTyrRS (Y341A) (100 μg/kg)

Blood sampling in every day

rhTyrRS (Y341A) (100 μg/kg)

Blood sampling in every day

TPO (300U/kg, positive control)

TPO (300U/kg, positive control)