Figure 5
From: Serial-omics of P53−/−, Brca1−/− Mouse Breast Tumor and Normal Mammary Gland
Results from the protein pellet. (A) A bar plot of a portion of the most regulated proteins from the breast tumor vs. mammary gland experiment. Down-regulated proteins, such as PLIN1 and ACSA in breast tumor tissue are involved in lipid metabolism. (B) The profile for biological processes with fold enrichment across all down-regulated proteins including p-values generated with the Panther Classification System. (C) The profile for biological processes with fold enrichment across all up-regulated proteins including p-value generated with Panther Classification System. (D) A bar plot with all detected proteins involved in the mTOR pathway. (E) A bar blot representing the total protein levels in both breast tumor and mammary gland tissue by summing the MS2 total ion count intensity over all identified proteins (peptides).
