Table 2 Neutralization activity of mAbs against A(H1N1)pdm09 viruses.

From: Diversity of antigenic mutants of influenza A(H1N1)pdm09 virus escaped from human monoclonal antibodies

mAb

IC50 value (μg/ml) against A(H1N1)pdm09 virus isolated in

2009a

2010–2011b (Clade 5h)

2011–2012c (Clade 7)

2012–2013d (Clade 6C)

2013–2014e (Clade 6B)

2014–2015f (Clade 6B)

2015–2016g (Clade 6B.1)

1429B72/2-7

0.10

0.08

0.12

0.10

>50

>50

>50

1429C45/1-5

0.39

0.25

0.31

0.39

>50

>50

>50

CR9114

6.25

3.94

3.94

9.92

0.92

1.24

1.24

  1. aA/California/04/2009, bA/Hiroshima/66/2011, cA/Osaka/83/2011, dA/Osaka/33/2013, eA/Osaka/6/2014, fA/Yokohama/50/2015 and gA/Yokohama/94/2015 were used in this experiment.
  2. hPhylogenetic clades are listed for each isolate.
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