Table 4 National Eye Institute Visual Function (NEI-VFQ-25) questionnaire scores and number of eyes with visual field damage: statistical analysis (per-patient analysis).

From: Visual field loss and vision-related quality of life in the Italian Primary Open Angle Glaucoma Study

 

Intercept

VFD-1

VFD-2

Age

BCVA

Previous treatment

β (Stderr)

p-value

β (Stderr)

p-value*

β (Stderr)

p-value*

β (Stderr)

p-value

β (Stderr)

p-value

β (Stderr)

p-value

General health

67.99 (2.91)

<0.001

−1.25 (1.13)

0.268

−3.76 (1.02)

<0.001

−0.16 (0.03)

<0.001

5.59 (1.67)

<0.001

−2.45 (1.20)

0.041

General vision

47.98 (2.42)

<0.001

−2.06 (0.94)

0.029

−6.49 (0.85)

<0.001

0 (0.02)

0.973

25.04 (1.39)

<0.001

−3.53 (1.00)

<0.001

Ocular pain

68.37 (3.29)

<0.001

−1.36 (1.28)

0.289

−3.13 (1.16)

0.007

0.08 (0.03)

0.021

12.47 (1.89)

<0.001

−3.81 (1.36)

0.005

Near activities

63.44 (2.97)

<0.001

−1.59 (1.16)

0.170

−5.85 (1.05)

<0.001

0 (0.03)

0.876

30.53 (1.7)

<0.001

−2.36 (1.22)

0.054

Distance activities

69.37 (2.53)

<0.001

−1.36 (0.99)

0.169

−4.84 (0.89)

<0.001

−0.01 (0.03)

0.737

29.03 (1.45)

<0.001

−1.21 (1.04)

0.244

Social functioning

82.18 (2.00)

<0.001

−0.09 (0.78)

0.907

−2.12 (0.71)

0.003

−0.03 (0.02)

0.196

19.83 (1.15)

<0.001

−0.94 (0.82)

0.255

Mental health

58.59 (3.14)

<0.001

−2.08 (1.22)

0.088

−5.57 (1.11)

<0.001

0.08 (0.03)

0.009

27.42 (1.8)

<0.001

−4.9 (1.29)

<0.001

Role difficulties

68.99 (2.98)

<0.001

−1.32 (1.16)

0.257

−4.65 (1.05)

<0.001

0.01 (0.03)

0.665

30.08 (1.71)

<0.001

−3.07 (1.23)

0.012

Dependency

77.4 (2.8)

<0.001

−0.4 (1.09)

0.714

−3.26 (0.99)

0.001

−0.05 (0.03)

0.104

25.8 (1.61)

<0.001

−1.03 (1.15)

0.370

Driving

67.31 (4.23)

<0.001

−4.1 (1.56)

0.009

−7.29 (1.42)

<0.001

−0.08 (0.04)

0.043

32.7 (2.55)

<0.001

−2.56 (1.76)

0.146

Color vision

85.18 (2.32)

<0.001

−0.42 (0.9)

0.642

−2.12 (0.81)

0.009

−0.04 (0.02)

0.110

18.23 (1.33)

<0.001

−1.3 (0.95)

0.172

Peripheral vision

68.79 (3.31)

<0.001

−3.18 (1.29)

0.013

−6.7 (1.16)

<0.001

0 (0.03)

0.971

30.93 (1.89)

<0.001

−3.11 (1.36)

0.022

Total score

68.69 (2.16)

<0.001

−1.58 (0.84)

0.060

−4.7 (0.76)

<0.001

0 (0.02)

0.944

25.57 (1.24)

<0.001

−2.56 (0.89)

0.004

  1. SD, standard deviation; VFD-1, patients with visual field damage in one eye; VFD-2, patients with visual field damage in both eyes; BCVA, best corrected visual acuity; β, beta coefficient; SE, standard error for beta coefficient; p-value for multivariate linear regression model including visual field damage groups, BCVA, age, previous treatment (treated versus untreated); *, p-values for VFD-1 and VFD-2 refer to the comparison between each group and VFD-0 (patients without visual field damage in any eye).
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