Figure 7 | Scientific Reports

Figure 7

From: Ormeloxifene-induced unfolded protein response contributes to autophagy-associated apoptosis via disruption of Akt/mTOR and activation of JNK

Figure 7

ORM administration reduces tumor progression and promotes autophagy in vivo. Reduction in both (A) tumor volume, and, (B) tumor mass was achieved when ORM (50 mg/kg body weight) was administered for 4 weeks. (C) LC3-II induction as a marker for autophagy activity in tumors isolated from control (VC) and ORM-treated (ORM) mice.

Back to article page