Table 1 The binding rates to target and non-target cells of the different groups.

From: Preparation and Imaging Investigation of Dual-targeted C3F8-filled PLGA Nanobubbles as a Novel Ultrasound Contrast Agent for Breast Cancer

Cells

Non-targeted NBs

Single-targeted NBs

Dual-targeted NBs

SKBR3

2.17 ± 0.56

70.16 ± 3.28*‡

74.59 ± 3.47*‡

SVR

2.35 ± 0.66

73.49 ± 3.67*‡

78.41 ± 3.41*‡

MDA-MB-231

1.58 ± 0.24

2.28 ± 0.72

2.37 ± 1.21

4T1

1.81 ± 0.39

2.74 ± 1.03

3.24 ± 1.16

  1. Note—data in table are percentages.
  2. *Significantly different from the cells treated with non-targeted NBs (*P < 0.001).
  3. ‡Significantly different from MDA-MB-231 or 4T1 cells treated with single or dual-targeted NBs (‡P < 0.001).
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