Figure 2

LI-rTMS affects late VEP response peak amplitudes only in wildtypes with concurrent visual input. (A) Mean VEP response to flashed grating after LI-rTMS or sham applied with visual input or (B) in the dark. Genotypes and stimulation conditions are shown separately with pre- and post-stimulation traces overlaid. Dashed line box represents boundaries defining ‘Early response’ window, and solid box represents ‘Late response’ window in which peak amplitudes were analysed (peak boundary windows were defined for each subject separately). (C–F) Pre- and post-stimulation mean (±SEM) peak amplitudes for (C) early response positive peak, P1, and (D) early response major negative peak, N1; (E) the largest positive peak in the late response window; and (F) largest negative peak within the late response window. Note reversed sign on negative peak axes: up represents larger peak on all graphs. Significant interactions (RM-ANOVA) are noted in each graph, with significance level denoted as: *p < 0.05, **p < 0.01. Coloured symbols show significance levels for each separate follow-up tests for simple effects (Sidak corrected). *p < 0.05, **p < 0.01, visual input groups sham vs. LI-rTMS; ^#p < 0.05, ^##p < 0.01, ^###p < 0.001, pre-stimulation vs. post-stimulation, colour and position on graph denotes group; +p < 0.05, ++p < 0.01, change between pre- and post-stimulation LI-rTMS vs. sham (see also Fig. S1 for graphs expressing amplitudes as the difference between post- to pre-stimulation values).