Figure 1

CBF of diabetic rats during ET surgery. (A) The diabetes and ET tMCAO model in rats. Rats received 60 mg/kg streptozotocin (STZ) intraperitoneally. Four weeks later, the rats received 30 mg/kg Rivaroxaban or saline orally. (B) Laser Doppler measurements during tMCAO surgery in diabetic control rats (n = 33, full line) and Rivaroxaban-treated diabetic rats (n = 33, dash line).