Figure 2
From: Genetic Determinants of Telomere Length in African American Youth

Results of GWAS for TL in healthy African American children and adolescents in SAGE: San Francisco Bay Area, 2006–2015. (A) Manhattan plot of the GWAS of TL with three SNPs relevant to telomere biology highlighted. Genome-wide significance threshold is indicated as red line (P = 1.2 × 10−7) and suggestive significance threshold is indicated as blue line (P = 2.3 × 10−6). (B) Expansion of 1 Mb flanking region around the top hit (rs1483898) with surrounding SNPs colored by amount of linkage disequilibrium with the top SNP, indicated by pairwise r2 values from hg19/November 2014 1000 Genomes AFR.