Figure 2 | Scientific Reports

Figure 2

From: N-Phenylquinazolin-2-amine Yhhu4952 as a novel promotor for oligodendrocyte differentiation and myelination

Figure 2

Yhhu4952 inhibits the proliferation of OPCs without affecting cell viability or apoptosis. (a) Effects of Yhhu4952 on OPCs viability were assessed by Cell Counting Kit-8. (b) TUNEL staining (red) following various Yhhu4952 concentration treatment. (c) Quantification of TUNEL+/DAPI cells. (d) BrdU incorporation assay was performed in OPC culture. Cells were immunostained with BrdU (red). (e) Quantification of BrdU+/DAPI cells. Data are analyzed using one-way ANOVA and displayed as mean ± SEM of three independent experiment. *p < 0.05, **p < 0.01, ***p < 0.001 compared with control. Scale bar = 50 μm.

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