Figure 6

A schematic of the experimental design. The gray boxes indicate that mice received a common diet, and blue boxes indicate that mice were treated with L. reuteri HCM2. The red arrow indicates when mice were challenged with ETEC. Control: mice received a basal diet. HCM2: mice received a basal diet and 109 CFUs L. reuteri HCM2 daily for two consecutive weeks. ED1: mice received a basal diet, were challenged with 108 CFUs ETEC by intragastric administration at day 15, then received a basal diet for 1 day. HED1: mice received a basal diet and 109 CFUs L. reuteri HCM2 daily for two consecutive weeks, were challenged with 108 CFUs ETEC by intragastric administration at day 15 and then received a basal diet for 1 day. ED3: mice received a basal diet, were challenged with 108 CFUs ETEC by intragastric administration at day 15, then received a basal diet for 3 days. HED3: mice received a basal diet and 109 CFUs L. reuteri HCM2 daily for two consecutive weeks, were challenged with 108 CFUs ETEC by intragastric administration at day 15, and then received a basal diet for 3 days.