Figure 7 | Scientific Reports

Figure 7

From: Astragaloside IV inhibits glucose-induced epithelial-mesenchymal transition of podocytes through autophagy enhancement via the SIRT–NF-κB p65 axis

Figure 7

AS-IV effects on renal function and morphology in diabetic KK-Ay mice. (A,B) Renal function was evaluated by the levels of ACR and mAlb. (C) Light and electronic microscopy (EM) was used to observe renal morphologies. Representative photographs are shown for EM, hematoxylin-eosin (HE), masson and Periodic Acid-Schiff (PAS) staining. (D) AS-IV effects on Col IV and FN expressions in diabetic KK-Ay mice. Representative photographs of IHC are depicted for FN and col-IV. Data is presented as mean ± SD. n = 12. *Compared with normal control cohort or AS-IV treated cohort, P < 0.05.

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