Figure 2 | Scientific Reports

Figure 2

From: DGAT1 Inhibitor Suppresses Prostate Tumor Growth and Migration by Regulating Intracellular Lipids and Non-Centrosomal MTOC Protein GM130

Figure 2

DGAT1 inhibitor reduces cell proliferation and migration in prostate cancer cells. LNCaP and PC-3 cells were treated with 1 µM DGAT1 inhibitor for 24 h. (A) The proliferation rate was evaluated by the percentage of cells positive for PCNA staining/total cells (n = 50). The migration rate was evaluated by the percentage of (B) LNCaP cells and (C) PC-3 cells able to move into the scratched area at the times of 12 and 36 h. (D) Cell invasion was analyzed at the time of 24 h. Data are presented as mean ± SEM. Student’s unpaired t test. *P < 0.05, ***P < 0.001, ****P < 0.0001.

Back to article page