Figure 4

Metabolite profiles in selected tissues during Py infection. Principal Component Analysis (PCA) plot showing similarity of metabolite profiles in Tac and CR samples in the small intestine (A), cecum (C), and plasma (E). Ellipses contain the 90% confidence area of each group. Metabolite profile heatmap from the small intestine (B), cecum (D), and plasma (F). Sample group averages and metabolites are clustered using Ward’s method and Euclidean distance measure. Data are the cumulative results of 2 experiments (3 mice/group/experiment). Scale bar represents scaled relative abundance of metabolites.