Table 1 Clinical features of patients on the waiting list divided according to the study population.
|  | Meeting Bologna down-staging criteria (n = 122) | T2 group MC | P | ||
|---|---|---|---|---|---|
Down-staging completed | Down- staging not completed | Down- staging not performed | |||
Down-Achieved | Down-No Achieved | No-Down | |||
(n = 65) | (n = 30) | (n = 27) | (n = 186) | ||
Male, n (%) | 60 (92.3) | 26 (86.7) | 18 (66.7) | 160 (86.0) | p = 0.02 |
Age y, mean ± SD (median) | 56 ± 9 (57) | 55 ± 11 (57) | 56 ± 7 (57) | 57 ± 8 (59) | p = 0.3 |
Liver disease HCV + , n (%) | 36 (55.5) | 21 (70.0) | 18 (66.7) | 109 (58.6) | p = 0.1 |
CHILD C, n (%) | 13 (20.0) | 5 (16.7) | 15 (55.6) | 44 (23.8) | p = 0.001 |
MELD, mean ± SD (median) | 13 ± 6 (11) | 13 ± 5 (14) | 16 ± 6 (17) | 13 ± 5 (13) | p = 0.05 |
AFP ng/dl median | 9 | 10 | 10 | 10 | p = 0.37 |
Waiting time median days | 362 | 180 | 141 | 285 | p = 0.7 |
Single HCC, n (%) | 6 (9.2) | 0 | 14 (51.9) | 96 (51.6) | p = 0.001 |
2 HCC, n (%) | 16 (24.6) | 9 (30.0) | 8 (29.6) | 51 (27.4) | |
3 HCC, n (%) | 11 (16.9) | 3 (10.0) | 5 (18.5) | 39 (19.9) | |
4 HCC, n (%) | 15 (23.1) | 14 (46.7) | — | — | |
5 HCC, n (%) | 17 (26.1) | 4 (13.3) | — | — | |
1 HCC mean size ± SD (median) | 3.7 ± 1.6 (4) | 3.6 ± 1.3 (3.9) | 2.8 ± 1.1 | 2.5 ± 0.9 | p = 0.001 |
2 HCCs mean size ± SD (median) | 2 ± 1 (1.9) | 2.3 ± 0.9 (2.3) | 1.3 ± 1.2 | 1.1 ± 0.9 | p = 0.001 |
3 HCCs mean size ± SD (median) | 1.4 ± 1.1 (1.2) | 1.4 ± 1.1 (1.1) | 0.8 ± 0.7 | 0.8 ± 0.7 | p = 0.001 |
4 HCCs mean size ± SD (median) | 1.1 ± 0.8 (1) | 0.9 ± 0.7 (1) | — | — | p = 0.001 |
5 HCCs mean size ± SD (median) | 1 ± 1.8 (1) | 0.8 ± 0.5 (0.6) | — | — | p = 0.001 |
Pre-LT Treatment, n (%) | 65 (100) | 30 (100) | 21 (77.8) | 167 (89.8) | p = 0.001 |
TACE, n (%) mean ± SD procedure | 52 (80.0) 1.7 ± 1.2 | 28 (93.3) 1.7 ± 1.3 | 18 (66.7) 1.7 ± 1.0 | 118 (63.4) 1.8 ± 1.0 | p = 0.002 |
PEI mean ± SD procedure | 19 (29.2) 1.2 ± 0.4 | 8 (26.7) 1.1 ± 0.4 | 3 (11.1) 1.0 ± 0 | 37 (19.9) 1.2 ± 1.0 | p = 0.19 |
RF mean ± SD procedure | 28 (43.1) 1.5 ± 1.3 | 9 (30.0) 0.9 ± 0.3 | 8 (29.6) 1.1 ± 0.4 | 65 (34.9) 1.3 ± 0.9 | p = 0.49 |
LR for down-stage | 18 (27.7) | 4 (13.8) | — | — | p = 0.001 |
Previous R0 LR | — | — | 3 (11.1) | 26 (14.1) | P = 0.005 |
