Figure 5
From: Molecular architecture of the Jumonji C family histone demethylase KDM5B
HDX-MS heatmap of KDM5B residues 740–1544. Top line above the numbering show annotated domains. The second line show the amino acid sequence numbers with the PLU region 768–1100 boxed. Third line shows the amino acid sequence. Fourth line shows the sequence-only derived secondary structure by the RaptorX server with α-helices represented by curvy line and β-strands represented by arrows. The fifth line shows the HDX-MS 15 seconds exchange heat map for KDM5B with the same coloring scheme as in Fig. 1. Sixth line shows the predicted coiled coil propensity using the COILS server with same color gradient as for the HDX-MS data with color mapping red as high propensity and blue low.
